Follow us on
Welcome Guest! You are here: Home » Healh
Artificial anti-cancer molecules created in a jiffy
Monday August 4, 2014 2:21 PM, IANS

In what could lead to new anti-cancer drugs, researchers have developed a new method to produce molecules that have a similar structure to peptides which are naturally produced in the body to fight cancer and infection.

The peptide mimics have been found to be successful in laboratory tests on colon cancer cells, the study said.

The new peptide mimics, called triplexes, have a similar 3D helix form to natural peptides.

Artificial peptides had previously been difficult and prohibitively expensive to manufacture in large quantities, but the new process takes only minutes and does not require costly equipment.

"The beauty is that these big molecules assemble themselves. Nature uses this kind of self-assembly to make complex asymmetric molecules like proteins all the time, but doing it artificially is a major challenge," said professor Peter Scott at the University of Warwick in Britain.

Traditional peptides that are administered as drugs are quickly neutralised by the body's biochemical defences before they can do their job.

A form of complex chemical self-assembly, the new method developed at Warwick addresses this problem by producing very stable molecules.

"The chemistry involved is like throwing Lego blocks into a bag, giving them a shake, and finding that you made a model of the Death Star," Scott said.

"The design to achieve that takes some thought and computing power, but once you have worked it out the method can be used to make a lot of complicated molecular objects," he said.

The study appeared in the journal Nature Chemistry.



Share this page
 Comments
Note: By posting your comments here you agree to the terms and conditions of www.ummid.com
comments powered by Disqus
Advertisement
| Quick links
About ummid.com
Contact us
Feedback
Subscribe to: RSS » Facebook » Twitter » Newsletter
Ummid.com: Disclaimer | Terms of Use | Advertise with us | Link Exchange
Ummid.com is part of the Awaz Multimedia & Publications providing World News, News Analysis and Feature Articles on Education, Health. Politics, Technology, Sports, Entertainment, Industry etc. The articles or the views displayed on this website are for public information and in no way describe the editorial views. The users are entitled to use this site subject to the terms and conditions mentioned.
© 2012 Awaz Multimedia & Publications. All rights reserved.