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Calcium
supplements cause heart problems in women?
Monday April 25, 2011 09:10:12 AM,
IANS
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Sydney:
There is growing evidence that calcium supplements increase the
risk of heart attacks among older women, say researchers.
Calcium supplements are often prescribed to older (postmenopausal)
women to maintain bone health. High blood calcium levels are
linked to calcification (hardening) of the arteries, which may
also help to explain these results.
Though the Women's Health Initiative (WHI) study, a seven-year
trial of over 36,000 women, found no cardiovascular effect of
taking combined calcium and vitamin D supplements, but a team led
by Prof Ian Reid at the University of Auckland, re-analysed the
WHI results to evaluate the effects of calcium supplements, with
or without vitamin D, on the risk of cardiovascular events, the
British Medical Journal reports, citing an Auckland varsity
statement.
Reid's team analysed data from 16,718 women who were not taking
personal calcium supplements at the start of the trial and found
that those allocated to combined calcium and vitamin D supplements
were at an increased risk of cardiovascular events, especially
heart attack.
Conversely, in women who were taking personal calcium supplements
at the start of the trial, combined calcium and vitamin D
supplements did not alter their usual cardiovascular risk.
The authors suspect that the abrupt change in blood calcium levels
after taking a supplement causes the adverse effect, rather than
it being related to the total amount of calcium consumed.
Further analyses -- adding data from 13 other trials, involving
29,000 people altogether -- also found consistent increases in the
risk of heart attack and stroke associated with taking calcium
supplements, with or without vitamin D.
These analyses led the study authors to conclude that these data
justify a reassessment of the use of calcium supplements in older
people.
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