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New treatment could halt arthritis spread
Tuesday July 31, 2012 11:00:29 PM,
IANS
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Sydney: Researchers
have developed a potential new approach to treat chronic diseases
such as arthritis, which involves the inflammation of one or more
bone joints.
David Fairlie and his colleagues from The University of
Queensland's Institute for Molecular Bioscience have developed an
experimental treatment that effectively eases symptoms and stops
the progression of the disease.
"Human enzymes called proteases stimulate the secretion of immune
cells that, when the correct amount is released, play important
roles in digestion, fighting infections and healing wounds,"
Fairlie was quoted as saying in the journal The Federation of
American Societies For Experimental Biology.
"But in chronic inflammatory diseases such as arthritis, these
enzymes continuously stimulate the release of immune cells, which
cause inflammation when present at high levels. This leads to
ongoing tissue damage," added Fairlie. Inflammation is the body's
response to an injury, infection or illness, according to a
Queensland statement.
Fairlie and his team have developed experimental compounds that
block this stimulation and successfully reduce chronic
inflammatory arthritis in experimental models.
If the treatment could be transferred to humans, it has the
potential to reduce both the health and economic impacts of
chronic inflammatory diseases.
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