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Drug-free approach to ease blood pressure in
offing
Wednesday October 31, 2012 05:37:43 PM,
IANS
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Washington: Researchers are working on a drug-free approach to normalising
high blood pressure linked to stroke, heart and kidney diseases.
The Symplicity trial tests a minimally invasive procedure known as
renal denervation. The experimental procedure uses heat that is
generated by radio frequency to disrupt nerve communication to and
from the kidneys.
This can reduce hyperactivity in the sympathetic nervous system, a
frequent cause of chronic high BP.
"The sympathetic nervous system controls blood pressure and can
cause hypertension initiated by life and stress," said David L.
Brown, principal investigator at The Heart Hospital Baylor Plano,
US.
"This investigational device is being tested to determine if it
will disrupt the sympathetic nervous system, which may
significantly lower blood pressure, stop multiple
anti-hypertensive medications, and have an effect on other
conditions affected by the sympathetic nervous system," added
Brown, according to a Baylor statement.
Blood pressure is measured in millimetres of mercury (mmHg). A
pressure at or less than 120/80 is considered healthy.
"In previous studies of this device in limited numbers of people,
this simple procedure reduced patients' blood pressure by an
average of about 30 mmHg, a reduction that persisted throughout
subsequent assessments," said Sonia Parashar, research coordinator
at The Heart Hospital.
Baylor Jack and Jane Hamilton Heart and Vascular Hospital also is
participating in the study.
"Improving blood pressure has a profound effect on longevity and
reducing the risk of stroke," said James W. Choi, primary
investigator for the Symplicity trial at Baylor Heart and Vascular
Hospital.
"Catheter-based renal denervation is an exciting, investigational
treatment for patients with resistant hypertension who otherwise
might not be able to be helped," added Choi.
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