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Found! Brain tumour culprit
Monday October 24, 2011 03:13:19 PM,
IANS
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Sydney:
Scientists have pinned down a culprit that allows brain tumours to
survive and grow.
An international team identified the key role played by kynurenine,
by-product of the metabolism of amino acid tryptophan, in brain
tumour growth, the journal Nature reports.
The discovery offers hope of new drug treatment for gliomas -- the
most common and aggressive type of brain tumour in both adults and
children. The survival time of patients is less than a year.
Gilles Guillemin, an associate professor with the University of
New South Wales, said the breakthrough could potentially lead to
viable therapeutics for a range of conditions.
These conditions include Alzheimer's disease, motor neuron
diseases, multiple sclerosis and Parkinson's disease, according to
a New South Wales statement.
An oral drug able to block enzymes leading to kynurenine
production has been developed. It could potentially be available
for clinical trials within a few years, Guillemin said.
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