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Faulty gene spikes prostate cancer risk in men
Monday April 23, 2012 08:44:30 AM,
IANS
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London: A faulty
gene that increases breast cancer risk in women also quadruples
the chances of prostate cancer among men, says a recent study.
"Until now, there has been some doubt as to whether mutations in
the BRCA1 gene increase the risk of prostate cancer," said Ros
Eeles, professor at the Institute of Cancer Research in London,
who conducted the research.
"Our study has shown that men with prostate cancer have a one in
200 chance of having an alteration of this gene and men with this
alteration have a 3.8 fold increased risk of developing the
disease," said Eeles, the British Journal of Cancer reports.
Men carrying a faulty BRCA1 gene have a one in 11 chance of
developing prostate cancer by 65 years, the study said. The faulty
gene seemed to be tied to a particularly aggressive form of cancer
making early detection and treatment vital, according to the
Telegraph.
In breast cancer, BRCA1 increases the chances of developing the
disease five-fold, giving them a six in 10 chance of breast cancer
compared with a one in eight chance for healthy women. It has led
some women with the faulty gene to have pre-emptive mastectomy
rather than live with high risk of breast cancer.
Emma Malcolm, chief executive of the charity Prostate Action,
which co-funded the study, said: "Early detection of prostate
cancer can vastly improve the chances of successful treatment but
at the moment there is no effective way of screening the disease."
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