Scientists find link between rheumatoid
arthritis and dental health
Wednesday October 17, 2012 11:17:27 AM,
IANS
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Sydney: Rheumatoid
arthritis patients are more likely to suffer tooth loss due to
periodontal disease, which manifests as sore and inflamed gums
which weaken the bone and tissues supporting the teeth.
Rheumatoid arthritis causes the immune system to attack healthy
tissue in the joints, leading to inflammation and loss of bone and
cartilage. This results in a painful condition which impacts
normal joint function.
"Not only did the gum disease influence joint tissues, but
arthritis also influenced tissues in the mouth," said doctoral
candidate Melissa Cantley, who worked with colleagues at the
University of Adelaide.
"The relationship between these two common diseases is very
complex and we can now use this model to further our
understanding," said Melissa, whose doctoral supervisors are David
Haynes, associate professor and Bartold Mark, professor, at
Adelaide.
The research also found signs of bone loss in the joints of mice
with gum disease alone and bone loss in the jaws of mice with
arthritis alone, according to an Adelaide statement.
Clinical studies are underway to determine if treatment of
periodontitis can help reduce the symptoms tied to arthritis.
Cantley is one of 12 early-career scientists who are using this
knowledge to investigate whether treating mouth conditions could
help relieve arthritis.
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