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Chemical in plastic bottles aggravates heart risk
Thursday August 16, 2012 06:42:45 PM,
IANS
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London: The presence
of high levels of urinary Bisphenol-A (BPA), a chemical used in
plastic products like water bottles and baby feeding bottles, may
be linked to narrowing of arteries and risk of heart disease.
"Our latest study strengthens a growing body of work that suggests
that BPA may be adding to known risk factors for heart disease,"
said David Melzer, professor of epidemiology and public health at
Peninsula College of Medicine and Dentistry (PCMD) of Exeter
University.
A team led by Melzer from the PCMD and University of Cambridge
analysed data from 591 patients, who participated in the
Metabonomics and Genomics Coronary Artery Disease (MaGiCAD) study
in Cambridgeshire, UK, the journal Public Library of Science ONE
reports.
Patients were classified into severe, intermediate or normal
coronary artery disease (CAD) categories based on narrowing of
their coronary arteries, which deliver oxygen-rich blood to the
heart muscle known as myocardium, according to an Exeter
statement.
In all, 385 patients were identified to have severe CAD, 86
intermediate CAD and 120 had normal coronary arteries. The vessels
that deliver oxygen-rich blood to the myocardium are known as
coronary arteries.
The study shows that the concentration of urinary BPA, a
controversial chemical commonly used in food and drink containers,
was significantly higher in those with severe CAD compared to
those with normal coronary arteries.
Many nations moved to ban BPA from the manufacture of baby's
bottles and other feeding equipment, following a PCMD study in
September 2008. The BPA is used in polycarbonate plastic products
such as refillable drinks containers, compact disks, some plastic
eating utensils and many other products in everyday use.
Other studies related to BPA carried out by the same research team
have found associations with altered testosterone, suggesting that
the chemical may be more active in the body than previously
thought.
Tamara Galloway, professor of toxicology and study co-author from
Exeter, said: "These results are important because they give us a
better understanding of the mechanisms underlying the association
between BPA and heart disease."
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