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Active lifestyle helps slow dementia
Tuesday November 27, 2012 08:38:31 AM,
IANS
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Washington:
An active lifestyle helps preserve the brain's grey matter and
lowers the risk of dementia and Alzheimer's disease (AD), says a
new study.
More than 35 million people worldwide are living with dementia,
and the numbers are expected to double by 2030, according to the
World Health Organisation. AD is the most common cause of dementia
and is incurable.
"The grey matter volume is a key marker of brain health. Larger
grey matter volume means a healthier brain. Shrinking volume is
seen in Alzheimer's disease," said Cyrus Raji, radiology resident
at the University of California in Los Angeles (UCLA), who
conducted the study.
Raji and colleagues recently examined how an active lifestyle can
influence brain structure.
They studied 876 adults of an average age of 78 years, drawn from
the multisite Cardiovascular Health Study. The patients'
conditions ranged from normal cognition to Alzheimer's dementia,
according to an UCLA statement.
"We had 20 years of clinical data on this group, including body
mass index and lifestyle habits," Raji said. "We drew our patients
from four sites across the country, and we were able to assess
energy output in the form of kilocalories per week."
The lifestyle factors examined included recreational sports,
gardening and yard work, bicycling, dancing and riding exercise
cycle.
"The areas of the brain that benefited from an active lifestyle
are the ones that consume the most energy and are very sensitive
to damage," Raji added.
"What struck me most about the study results is that it is not one
but a combination of lifestyle choices and activities that benefit
the brain," Raji said.
"Virtually all of the physical activities examined in this study
are some variation of aerobic physical activity, which we know
from other work can improve cerebral blood flow and strengthen
neuronal (brain cell) connections," he said.
Researchers used magnetic resonance imaging (MRI) and a technique
called voxel-based morphometry, "an advanced method that allows a
computer to analyze an MR image and build a mathematical model
that helps us understand the relationship between active lifestyle
and gray matter volume," said Raji.
These findings were presented at the annual meeting of the
Radiological Society of North America (RSNA).
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